Home  Medical Use Law & Legislation Cannabinoids Enhance Analgesic Effects of Anti-Inflammatory Drugs
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Cannabinoids Enhance Analgesic Effects of Anti-Inflammatory Drugs |
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Ankara, Turkey: Cannabinoids, when administered in combination with non-steroidal anti-inflammatory drugs (NSAIDS), produce a synergistic analgesic effect, according to preclinical data published in the February 2006 issue of the journal Anesthesia & Analgesia.
A research team at the Trakya University in Turkey investigated the analgesic interaction between cannabinoids and NSAIDS in mice. "Analysis showed additive interactions between [cannabinoids] and [NSAIDS] when they were co-administered systematically in an inflammatory visceral pain model," investigators concluded. "The combination of cannabinoids and NSAIDS may have utility in the pharmacotherapy of pain."
Currently, a research team at the San Francisco General Hospital in California is evaluating the
effectiveness of inhaled cannabis when used as an adjunctive therapy in combination with opioids to treat persistent cancer pain. The findings of that clinical trial are expected to be published later this year.
Full text of the Turkish study, "The additive antinociceptive interaction between WIN 55,212-2, a cannabinoid agonist, and Ketorolac," appears in the journal Anesthesia & Analgesia. |
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